Introduction to Knee Osteoarthritis and Its Epidemiology

Knee osteoarthritis, or OA, additionally referred to as a degenerative joint disease, is generally the outcome of damage as well as dynamic loss of articular cartilage. It is most usual in elderly individuals, as well as can be divided into two kinds, primary as well as secondary:

The main osteoarthritis is articular deterioration without any apparent underlying cause.

Secondary osteoarthritis is the effect of either an unusual concentration of pressure throughout the joint as with post-traumatic causes or unusual articular cartilage material, such as rheumatoid joint inflammation, or RA.

Osteoarthritis is an uncomfortable, chronic joint condition that largely influences not just the knees; however, also the hands, hips, as well as spine. The strength of the signs and symptoms vary for each person and usually advance gradually.

Typical scientific symptoms include:

  • Knee discomfort that is progressive in beginning as well as aggravates with activity
  • Pain after prolonged sitting or relaxing
  • Knee rigidity as well as swelling
  • Crepitus or a fracturing noise with joint motion

Treatment for knee osteoarthritis starts with conventional methods and advances to medical therapy alternatives when traditional treatment falls short. While medicines can assist to reduce the progression of RA and various other inflammatory conditions, there are no tried and tested disease-modifying representatives for the therapy of knee OA.


OA is amongst the most typical disease of the joints worldwide, with the knee being amongst the most commonly influenced joints in the body. It mainly impacts individuals over the age of 45.

OA can cause pain as well as loss of function, yet not everyone with radiographic searching for knee OA will be symptomatic: in one study just 15% of patients with radiographic findings of knee OA were symptomatic.

  • OA influences almost 6% of all grownups.
  • Females are more typically influenced than men. Roughly 13% of females, as well as 10% of guys 60 years and older, have symptomatic knee osteoarthritis.
  • Amongst those older than 70 years of age, the prevalence increases to as high as 40%. And will continue to increase as life expectancy as well as obesity surges.

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